Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more


pMRXIP GFP-Stx17 WT Citations (7)

Originally described in: The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
Itakura E, Kishi-Itakura C, Mizushima N Cell. 2012 Dec 7;151(6):1256-69. doi: 10.1016/j.cell.2012.11.001.
PubMed Journal

Articles Citing pMRXIP GFP-Stx17 WT

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation. Nguyen TN, Padman BS, Usher J, Oorschot V, Ramm G, Lazarou M. J Cell Biol. 2016 Dec 19;215(6):857-874. Epub 2016 Nov 18. PubMed

Associated Plasmids

BORC coordinates encounter and fusion of lysosomes with autophagosomes. Jia R, Guardia CM, Pu J, Chen Y, Bonifacino JS. Autophagy. 2017 Oct 3;13(10):1648-1663. doi: 10.1080/15548627.2017.1343768. Epub 2017 Aug 21. PubMed
STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism. Xian H, Yang Q, Xiao L, Shen HM, Liou YC. Nat Commun. 2019 May 3;10(1):2059. doi: 10.1038/s41467-019-10096-1. PubMed
CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis. An HK, Chung KM, Park H, Hong J, Gim JE, Choi H, Lee YW, Choi J, Mun JY, Yu SW. Autophagy. 2019 Dec 10:1-20. doi: 10.1080/15548627.2019.1695398. PubMed
A SNARE protein Syntaxin 17 captures CFTR to potentiate autophagosomal clearance under stress. Arora K, Liyanage P, Zhong Q, Naren AP. FASEB J. 2021 Feb;35(2):e21185. doi: 10.1096/fj.201903210R. Epub 2020 Nov 15. PubMed
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components. Abudu YP, Shrestha BK, Zhang W, Palara A, Brenne HB, Larsen KB, Wolfson DL, Dumitriu G, Oie CI, Ahluwalia BS, Levy G, Behrends C, Tooze SA, Mouilleron S, Lamark T, Johansen T. J Cell Biol. 2021 Aug 2;220(8). pii: 212185. doi: 10.1083/jcb.202009092. Epub 2021 May 26. PubMed
High-resolution visualization and assessment of basal and OXPHOS-induced mitophagy in H9c2 cardiomyoblasts. Godtliebsen G, Larsen KB, Bhujabal Z, Opstad IS, Nager M, Punnakkal AR, Kalstad TB, Olsen R, Lund T, Prasad DK, Agarwal K, Myrmel T, Birgisdottir AB. Autophagy. 2023 Oct;19(10):2769-2788. doi: 10.1080/15548627.2023.2230837. Epub 2023 Jul 5. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.