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pcDNA-dCas9 Citations (11)

Originally described in: RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA Nat Methods. 2013 Jul 25. doi: 10.1038/nmeth.2600.
PubMed Journal

Articles Citing pcDNA-dCas9

Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression. Kabadi AM, Gersbach CA. Methods. 2014 Sep;69(2):188-97. doi: 10.1016/j.ymeth.2014.06.014. Epub 2014 Jul 8. PubMed
Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system. Garcia-Bloj B, Moses C, Sgro A, Plani-Lam J, Arooj M, Duffy C, Thiruvengadam S, Sorolla A, Rashwan R, Mancera RL, Leisewitz A, Swift-Scanlan T, Corvalan AH, Blancafort P. Oncotarget. 2016 Sep 13;7(37):60535-60554. doi: 10.18632/oncotarget.11142. PubMed
Drug-tunable multidimensional synthetic gene control using inducible degron-tagged dCas9 effectors. Kleinjan DA, Wardrope C, Nga Sou S, Rosser SJ. Nat Commun. 2017 Oct 30;8(1):1191. doi: 10.1038/s41467-017-01222-y. PubMed
Single plasmid systems for inducible dual protein expression and for CRISPR-Cas9/CRISPRi gene regulation in lactic acid bacterium Lactococcus lactis. Berlec A, Skrlec K, Kocjan J, Olenic M, Strukelj B. Sci Rep. 2018 Jan 17;8(1):1009. doi: 10.1038/s41598-018-19402-1. PubMed
Genome-wide tracking of dCas9-methyltransferase footprints. Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Scholer HR, Gnirke A, Ziller MJ, Meissner A. Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5. PubMed
Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance. Chung JY, Ain QU, Song Y, Yong SB, Kim YH. Genome Res. 2019 Sep;29(9):1442-1452. doi: 10.1101/gr.246900.118. PubMed
Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient. Dal-Pra S, Hodgkinson CP, Dzau VJ. PLoS One. 2019 Oct 17;14(10):e0223842. doi: 10.1371/journal.pone.0223842. eCollection 2019. PubMed
A CRISPR-Cas9 repressor for epigenetic silencing of KRAS. Liu J, Sun M, Cho KB, Gao X, Guo B. Pharmacol Res. 2021 Feb;164:105304. doi: 10.1016/j.phrs.2020.105304. Epub 2020 Nov 14. PubMed
Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity. Iorga A, Donovan K, Shojaie L, Johnson H, Kwok J, Suda J, Lee BT, Aghajan M, Shao L, Liu ZX, Dara L. J Biol Chem. 2021 Jan-Jun;296:100300. doi: 10.1016/j.jbc.2021.100300. Epub 2021 Jan 16. PubMed
Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma. Sgro A, Cursons J, Waryah C, Woodward EA, Foroutan M, Lyu R, Yeoh GCT, Leedman PJ, Blancafort P. Clin Epigenetics. 2023 Apr 29;15(1):73. doi: 10.1186/s13148-023-01482-0. PubMed
Retinoblastoma protein activity revealed by CRISPRi study of divergent Rbf1 and Rbf2 paralogs. Raicu AM, Castanheira P, Arnosti DN. bioRxiv. 2023 Jul 3:2023.05.19.541454. doi: 10.1101/2023.05.19.541454. Preprint. PubMed

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