pMSCV-IRES-GFP II (pMIG II) Citations (49)
Originally described in: Generation of T-cell receptor retrogenic mice.Holst J, Szymczak-Workman AL, Vignali KM, Burton AR, Workman CJ, Vignali DA Nat Protoc. 2006;1(1):406-17. PubMed Journal
Articles Citing pMSCV-IRES-GFP II (pMIG II)
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| Recruitment of calcineurin to the TCR positively regulates T cell activation. Dutta D, Barr VA, Akpan I, Mittelstadt PR, Singha LI, Samelson LE, Ashwell JD. Nat Immunol. 2016 Dec 12. doi: 10.1038/ni.3640. PubMed |
| Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes. Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC. Cell. 2018 Jan 25;172(3):549-563.e16. doi: 10.1016/j.cell.2017.11.043. Epub 2017 Dec 21. PubMed |
| Substrate Selectivity Check of the Ergothioneine Transporter. Tschirka J, Kreisor M, Betz J, Grundemann D. Drug Metab Dispos. 2018 Jun;46(6):779-785. doi: 10.1124/dmd.118.080440. Epub 2018 Mar 12. PubMed |
| MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway. Wilson KR, Liu H, Healey G, Vuong V, Ishido S, Herold MJ, Villadangos JA, Mintern JD. PLoS One. 2018 Jul 12;13(7):e0200540. doi: 10.1371/journal.pone.0200540. eCollection 2018. PubMed |
| SMAC mimetics promote NIK-dependent inhibition of CD4(+) TH17 cell differentiation. Rizk J, Kaplinsky J, Agerholm R, Kadekar D, Ivars F, Agace WW, Wong WW, Szucs MJ, Myers SA, Carr SA, Waisman A, Bekiaris V. Sci Signal. 2019 Aug 27;12(596). pii: 12/596/eaaw3469. doi: 10.1126/scisignal.aaw3469. PubMed |
| Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Almeida CF, Sundararaj S, Le Nours J, Praveena T, Cao B, Burugupalli S, Smith DGM, Patel O, Brigl M, Pellicci DG, Williams SJ, Uldrich AP, Godfrey DI, Rossjohn J. Nat Commun. 2019 Nov 20;10(1):5242. doi: 10.1038/s41467-019-12941-9. PubMed |
| Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Wei J, Long L, Zheng W, Dhungana Y, Lim SA, Guy C, Wang Y, Wang YD, Qian C, Xu B, Kc A, Saravia J, Huang H, Yu J, Doench JG, Geiger TL, Chi H. Nature. 2019 Dec;576(7787):471-476. doi: 10.1038/s41586-019-1821-z. Epub 2019 Dec 11. PubMed |
| Butyrophilin 2A1 is essential for phosphoantigen reactivity by gammadelta T cells. Rigau M, Ostrouska S, Fulford TS, Johnson DN, Woods K, Ruan Z, McWilliam HEG, Hudson C, Tutuka C, Wheatley AK, Kent SJ, Villadangos JA, Pal B, Kurts C, Simmonds J, Pelzing M, Nash AD, Hammet A, Verhagen AM, Vairo G, Maraskovsky E, Panousis C, Gherardin NA, Cebon J, Godfrey DI, Behren A, Uldrich AP. Science. 2020 Feb 7;367(6478). pii: science.aay5516. doi: 10.1126/science.aay5516. Epub 2020 Jan 9. PubMed |
| Long noncoding RNA FOXD2-AS1 enhances chemotherapeutic resistance of laryngeal squamous cell carcinoma via STAT3 activation. Li R, Chen S, Zhan J, Li X, Liu W, Sheng X, Lu Z, Zhong R, Chen L, Luo X, Hu Y, Ouyang Y, Liu T, Zhang Q, Zhang S. Cell Death Dis. 2020 Jan 20;11(1):41. doi: 10.1038/s41419-020-2232-7. PubMed |
| Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells. Kanasugi J, Hanamura I, Ota A, Karnan S, Lam VQ, Mizuno S, Wahiduzzaman M, Rahman ML, Hyodo T, Konishi H, Tsuzuki S, Hosokawa Y, Takami A. Cancer Sci. 2020 May;111(5):1663-1675. doi: 10.1111/cas.14386. Epub 2020 Apr 9. PubMed |
| CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs. Johnson DK, Magoffin W, Myers SJ, Finnell JG, Hancock JC, Orton TS, Persaud SP, Christensen KA, Weber KS. Front Immunol. 2021 Jan 19;11:561889. doi: 10.3389/fimmu.2020.561889. eCollection 2020. PubMed |
| PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition. Li K, Yuan Z, Lyu J, Ahn E, Davis SJ, Ahmed R, Zhu C. Nat Commun. 2021 May 12;12(1):2746. doi: 10.1038/s41467-021-22965-9. PubMed |
| Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified. Debackere K, Marcelis L, Demeyer S, Vanden Bempt M, Mentens N, Gielen O, Jacobs K, Broux M, Verhoef G, Michaux L, Graux C, Wlodarska I, Gaulard P, de Leval L, Tousseyn T, Cools J, Dierickx D. Nat Commun. 2021 Jun 17;12(1):3705. doi: 10.1038/s41467-021-24037-4. PubMed |
| The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core. Bloch NB, Wales TE, Prew MS, Levy HR, Engen JR, Walensky LD. Nat Commun. 2021 Aug 13;12(1):4932. doi: 10.1038/s41467-021-25200-7. PubMed |
| TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Muschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL. Nat Commun. 2021 Sep 9;12(1):5337. doi: 10.1038/s41467-021-25622-3. PubMed |
| Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model. Wu C, Zhao J, Wu Q, Tan Q, Liu Q, Xiao S. Int J Mol Sci. 2021 Sep 8;22(18). pii: ijms22189728. doi: 10.3390/ijms22189728. PubMed |
| Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. Robles-Valero J, Fernandez-Nevado L, Lorenzo-Martin LF, Cuadrado M, Fernandez-Pisonero I, Rodriguez-Fdez S, Astorga-Simon EN, Abad A, Caloto R, Bustelo XR. EMBO J. 2021 Nov 15;40(22):e108125. doi: 10.15252/embj.2021108125. Epub 2021 Oct 7. PubMed |
| CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity. Long L, Wei J, Lim SA, Raynor JL, Shi H, Connelly JP, Wang H, Guy C, Xie B, Chapman NM, Fu G, Wang Y, Huang H, Su W, Saravia J, Risch I, Wang YD, Li Y, Niu M, Dhungana Y, Kc A, Zhou P, Vogel P, Yu J, Pruett-Miller SM, Peng J, Chi H. Nature. 2021 Dec;600(7888):308-313. doi: 10.1038/s41586-021-04109-7. Epub 2021 Nov 18. PubMed |
| Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination. Sun X, Bai J, Xu J, Xi X, Gu M, Zhu C, Xue H, Chen C, Dong J. Front Cell Dev Biol. 2021 Nov 26;9:767624. doi: 10.3389/fcell.2021.767624. eCollection 2021. PubMed |
| Differential antigenic requirements by diverse MR1-restricted T cells. Seneviratna R, Redmond SJ, McWilliam HE, Reantragoon R, Villadangos JA, McCluskey J, Godfrey DI, Gherardin NA. Immunol Cell Biol. 2022 Feb;100(2):112-126. doi: 10.1111/imcb.12519. Epub 2022 Jan 13. PubMed |
| Bamboo Shark as a Small Animal Model for Single Domain Antibody Production. Wei L, Wang M, Xiang H, Jiang Y, Gong J, Su D, Al Azad MAR, Dong H, Feng L, Wu J, Chan LL, Yang N, Shi J. Front Bioeng Biotechnol. 2021 Dec 8;9:792111. doi: 10.3389/fbioe.2021.792111. eCollection 2021. PubMed |
| Sex- and mutation-specific p53 gain-of-function activity in gliomagenesis. Rockwell NC, Yang W, Warrington NM, Staller MV, Griffith M, Griffith OL, Gurnett CA, Cohen BA, Baldridge D, Rubin JB. Cancer Res Commun. 2021 Dec;1(3):148-163. doi: 10.1158/2767-9764.crc-21-0026. PubMed |
| Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis. Wang W, Prokopec JS, Zhang Y, Sukhoplyasova M, Shinglot H, Wang MT, Linkermann A, Stewart-Ornstein J, Gong YN. Dev Cell. 2022 Jan 24;57(2):228-245.e6. doi: 10.1016/j.devcel.2021.12.015. Epub 2022 Jan 10. PubMed |
| Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86. Liu H, Wilson KR, Firth AM, Macri C, Schriek P, Blum AB, Villar J, Wormald S, Shambrook M, Xu B, Lim HJ, McWilliam HEG, Hill AF, Edgington-Mitchell LE, Caminschi I, Lahoud MH, Segura E, Herold MJ, Villadangos JA, Mintern JD. Nat Commun. 2022 Apr 11;13(1):1934. doi: 10.1038/s41467-022-29524-w. PubMed |
| A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells. Lim HJ, Wubben JM, Garcia CP, Cruz-Gomez S, Deng J, Mak JYW, Hachani A, Anderson RJ, Painter GF, Goyette J, Amarasinghe SL, Ritchie ME, Roquilly A, Fairlie DP, Gaus K, Rossjohn J, Villadangos JA, McWilliam HEG. J Cell Biol. 2022 Dec 5;221(12):e202110125. doi: 10.1083/jcb.202110125. Epub 2022 Sep 21. PubMed |
| Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2. Pymm P, Redmond SJ, Dolezal O, Mordant F, Lopez E, Cooney JP, Davidson KC, Haycroft ER, Tan CW, Seneviratna R, Grimley SL, Purcell DFJ, Kent SJ, Wheatley AK, Wang LF, Leis A, Glukhova A, Pellegrini M, Chung AW, Subbarao K, Uldrich AP, Tham WH, Godfrey DI, Gherardin NA. iScience. 2022 Nov 18;25(11):105259. doi: 10.1016/j.isci.2022.105259. Epub 2022 Oct 4. PubMed |
| Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape. Mangolini M, Maiques-Diaz A, Charalampopoulou S, Gerhard-Hartmann E, Bloehdorn J, Moore A, Giachetti G, Lu J, Roamio Franklin VN, Chilamakuri CSR, Moutsopoulos I, Rosenwald A, Stilgenbauer S, Zenz T, Mohorianu I, D'Santos C, Deaglio S, Hodson DJ, Martin-Subero JI, Ringshausen I. Nat Commun. 2022 Oct 20;13(1):6220. doi: 10.1038/s41467-022-33739-2. PubMed |
| Regulation of eIF4E guides a unique translational program to control erythroid maturation. Forester CM, Oses-Prieto JA, Phillips NJ, Miglani S, Pang X, Byeon GW, DeMarco R, Burlingame A, Barna M, Ruggero D. Sci Adv. 2022 Dec 23;8(51):eadd3942. doi: 10.1126/sciadv.add3942. Epub 2022 Dec 23. PubMed |
| Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs. Finnigan J, Newman J, Patskovsky Y, Patskovska L, Ishizuka A, Lynn G, Seder R, Krogsgaard M, Bhardwaj N. Res Sq. 2023 Jan 31:rs.3.rs-2531184. doi: 10.21203/rs.3.rs-2531184/v1. Preprint. PubMed |
| Runx3-overexpression cooperates with ex vivo AKT inhibition to generate receptor-engineered T cells with better persistence, tumor-residency, and antitumor ability. Tang J, Sheng J, Zhang Q, Ji Y, Wang X, Zhang J, Wu J, Song J, Bai X, Liang T. J Immunother Cancer. 2023 Feb;11(2):e006119. doi: 10.1136/jitc-2022-006119. PubMed |
| Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90beta. Chen SR, Li ZQ, Xu J, Ding MY, Shan YM, Cheng YC, Zhang GX, Sun YW, Wang YQ, Wang Y. Acta Pharmacol Sin. 2023 Aug;44(8):1637-1648. doi: 10.1038/s41401-023-01067-w. Epub 2023 Mar 7. PubMed |
| Aiolos represses CD4(+) T cell cytotoxic programming via reciprocal regulation of T(FH) transcription factors and IL-2 sensitivity. Read KA, Jones DM, Pokhrel S, Hales EDS, Varkey A, Tuazon JA, Eisele CD, Abdouni O, Saadey A, Leonard MR, Warren RT, Powell MD, Boss JM, Hemann EA, Yount JS, Xin G, Ghoneim HE, Lio CJ, Freud AG, Collins PL, Oestreich KJ. Nat Commun. 2023 Mar 24;14(1):1652. doi: 10.1038/s41467-023-37420-0. PubMed |
| Granulocyte-Macrophage Colony-Stimulating Factor Influence on Soluble and Membrane-Bound ICOS in Combination with Immune Checkpoint Blockade. Li X, Li J, Zheng Y, Lee SJ, Zhou J, Giobbie-Hurder A, Butterfield LH, Dranoff G, Hodi FS. Cancer Immunol Res. 2023 Aug 3;11(8):1100-1113. doi: 10.1158/2326-6066.CIR-22-0702. PubMed |
| Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase. Stadhouders LEM, Smith JAB, Gabriel BM, Verbrugge SAJ, Hammersen TD, Kolijn D, Vogel ISP, Mohamed AD, de Wit GMJ, Offringa C, Hoogaars WMH, Gehlert S, Wackerhage H, Jaspers RT. Exp Cell Res. 2023 Dec 15;433(2):113820. doi: 10.1016/j.yexcr.2023.113820. Epub 2023 Oct 23. PubMed |
T cell help shapes B cell tolerance.
Akama-Garren EH, Yin X, Prestwood TR, Ma M, Utz PJ, Carroll MC.
Sci Immunol. 2024 Feb 16;9(92):eadj7029. doi: 10.1126/sciimmunol.adj7029. Epub 2024 Feb 16.
PubMed
Associated Plasmids |
| Structural basis for self-discrimination by neoantigen-specific TCRs. Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Nat Commun. 2024 Mar 8;15(1):2140. doi: 10.1038/s41467-024-46367-9. PubMed |
| Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1. Wright T, Turnis ME, Grace CR, Li X, Brakefield LA, Wang YD, Xu H, Kaminska E, Climer LK, Mukiza TO, Chang CL, Moldoveanu T, Opferman JT. Mol Cell. 2024 Apr 4;84(7):1338-1353.e8. doi: 10.1016/j.molcel.2024.02.035. Epub 2024 Mar 18. PubMed |
| USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation. Zhao B, Xia Z, Yang B, Guo Y, Zhou R, Gu M, Liu M, Li Q, Bai W, Huang J, Zhang X, Zhu C, Leung KT, Chen C, Dong J. Cell Rep. 2024 May 28;43(5):114194. doi: 10.1016/j.celrep.2024.114194. Epub 2024 May 11. PubMed |
| The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Loh TJ, Lim JJ, Jones CM, Dao HT, Tran MT, Baker DG, La Gruta NL, Reid HH, Rossjohn J. Nat Commun. 2024 Jul 23;15(1):6201. doi: 10.1038/s41467-024-50511-w. PubMed |
| Parsing digital or analog TCR performance through piconewton forces. Akitsu A, Kobayashi E, Feng Y, Stephens HM, Brazin KN, Masi DJ, Kirkpatrick EH, Mallis RJ, Duke-Cohan JS, Booker MA, Cinella V, Feng WW, Holliday EL, Lee JJ, Zienkiewicz KJ, Tolstorukov MY, Hwang W, Lang MJ, Reinherz EL. Sci Adv. 2024 Aug 16;10(33):eado4313. doi: 10.1126/sciadv.ado4313. Epub 2024 Aug 14. PubMed |
| Direct recognition of an intact foreign protein by an alphabeta T cell receptor. Almeida CF, Gully BS, Jones CM, Kedzierski L, Gunasinghe SD, Rice MT, Berry R, Gherardin NA, Nguyen TT, Mok YF, Reijneveld JF, Moody DB, Van Rhijn I, La Gruta NL, Uldrich AP, Rossjohn J, Godfrey DI. Nat Commun. 2024 Oct 11;15(1):8816. doi: 10.1038/s41467-024-51897-3. PubMed |
| Retinoic acid and TGF-beta orchestrate organ-specific programs of tissue residency. Obers A, Poch T, Rodrigues G, Christo SN, Gandolfo LC, Fonseca R, Zaid A, Kuai JEY, Lai H, Zareie P, Yakou MH, Dryburgh L, Burn TN, Dosser J, Buquicchio FA, Lareau CA, Walsh C, Judd L, Theodorou MR, Gutbrod K, Dormann P, Kingham J, Stinear T, Kallies A, Schroeder J, Mueller SN, Park SL, Speed TP, Satpathy AT, Phan TG, Wilhelm C, Zaph C, Evrard M, Mackay LK. Immunity. 2024 Nov 12;57(11):2615-2633.e10. doi: 10.1016/j.immuni.2024.09.015. Epub 2024 Oct 14. PubMed |
| CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8(+) T cell formation. Raynor JL, Collins N, Shi H, Guy C, Saravia J, Ah Lim S, Chapman NM, Zhou P, Wang Y, Sun Y, Risch I, Hu H, Kc A, Sun R, Shrestha S, Huang H, Connelly JP, Pruett-Miller SM, Reina-Campos M, Goldrath AW, Belkaid Y, Chi H. Immunity. 2024 Nov 12;57(11):2597-2614.e13. doi: 10.1016/j.immuni.2024.09.013. Epub 2024 Oct 14. PubMed |
| IL-21 shapes the B cell response in a context-dependent manner. Kim Y, Manara F, Grassmann S, Belcheva KT, Reyes K, Kim H, Downs-Canner S, Yewdell WT, Sun JC, Chaudhuri J. Cell Rep. 2025 Jan 28;44(1):115190. doi: 10.1016/j.celrep.2024.115190. Epub 2025 Jan 9. PubMed |
| GATA2 mutated allele specific expression is associated with a hyporesponsive state of HSC in GATA2 deficiency syndrome. Largeaud L, Fregona V, Jamrog LA, Hamelle C, Dufrechou S, Prade N, Sellam E, Enfedaque P, Bayet M, Hebrard S, Bouttier M, Didier C, Gerby B, Delabesse E, Pasquet M, Broccardo C. Blood Cancer J. 2025 Jan 30;15(1):7. doi: 10.1038/s41408-025-01213-z. PubMed |
| PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1. Hong J, Sui P, Li Y, Xu KY, Lee JH, Wang J, Chen S, Zhang P, Wingate N, Noor A, Yuan Y, Hromas R, Zhou H, Hamamoto K, Su R, Yin CC, Ye F, Quesada AE, Chen J, Huang S, Zhou D, You MJ, Yang FC, Wang J, Xu M. Cell Stem Cell. 2025 Mar 6;32(3):463-478.e6. doi: 10.1016/j.stem.2025.01.010. Epub 2025 Feb 14. PubMed |
| VDAC2 loss elicits tumour destruction and inflammation for cancer therapy. Yuan S, Sun R, Shi H, Chapman NM, Hu H, Guy C, Rankin S, Kc A, Palacios G, Meng X, Sun X, Zhou P, Yang X, Gottschalk S, Chi H. Nature. 2025 Apr;640(8060):1062-1071. doi: 10.1038/s41586-025-08732-6. Epub 2025 Mar 19. PubMed |
| A naturally selected alphabeta T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide. Lim JJ, Jones CM, Loh TJ, Dao HT, Tran MT, Tye-Din JA, La Gruta NL, Rossjohn J. Nat Commun. 2025 Apr 8;16(1):3330. doi: 10.1038/s41467-025-58690-w. PubMed |
| Modeling the PAX5P80R Mutation Reveals HIF2alpha Activation as a Common Feature and Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia. Bayet M, Fregona V, Bouttier M, Rouzier C, Bigot J, Jamrog L, Hebrard S, Prade N, Lagarde S, Didier C, Gachet S, Passet M, Largeaud L, Pasquet M, Khamlichi AA, Clappier E, Delabesse E, Broccardo C, Gerby B. Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-1698. PubMed |
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