pcDNA3/Flag-WTAP Citations (8)

Originally described in: A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation.
Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C Nat Chem Biol. 2014 Feb;10(2):93-5. doi: 10.1038/nchembio.1432. Epub 2013 Dec 6. PubMed Journal

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Articles Citing pcDNA3/Flag-WTAP

Articles
Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m(6)A Methylation. Sun HL, Zhu AC, Gao Y, Terajima H, Fei Q, Liu S, Zhang L, Zhang Z, Harada BT, He YY, Bissonnette MB, Hung MC, He C. Mol Cell. 2020 Nov 19;80(4):633-647.e7. doi: 10.1016/j.molcel.2020.10.026. PubMed
mTORC1 promotes cell growth via m(6)A-dependent mRNA degradation. Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. Mol Cell. 2021 May 20;81(10):2064-2075.e8. doi: 10.1016/j.molcel.2021.03.010. Epub 2021 Mar 22. PubMed
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression. He RZ, Jiang J, Hu X, Lei M, Li J, Luo W, Duan L, Hu Z, Mo YY, Luo DX, Peng WX. Cancer Cell Int. 2021 Nov 22;21(1):616. doi: 10.1186/s12935-021-02288-x. PubMed
Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation. Han D, Longhini AP, Zhang X, Hoang V, Wilson MZ, Kosik KS. PLoS Biol. 2022 Feb 10;20(2):e3001535. doi: 10.1371/journal.pbio.3001535. eCollection 2022 Feb. PubMed
Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing. Cui X, Nilsson K, Kajitani N, Schwartz S. Virus Genes. 2022 Apr;58(2):98-112. doi: 10.1007/s11262-022-01889-6. Epub 2022 Feb 21. PubMed
Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension. Rao RJ, Yang J, Jiang S, El-Khoury W, Hafeez N, Okawa S, Tai YY, Tang Y, Al Aaraj Y, Sembrat J, Chan SY. bioRxiv [Preprint]. 2024 Sep 20:2024.09.19.613988. doi: 10.1101/2024.09.19.613988. PubMed
Poly-(ADP-ribose) serves as a scaffold for the methyltransferase METTL3/14 complex in the DNA damage response. Gonzalez-Leal C, Cai J, de Groot BAFJ, Wegerer A, Preisser J, Luijsterburg MS, Ladurner AG. Nucleic Acids Res. 2025 Apr 10;53(7):gkaf244. doi: 10.1093/nar/gkaf244. PubMed
Arginine methylation-dependent METTL14-SMN interaction regulates RNA m(6)A homeostasis. Zhang Y, Shen L, Ren L, Wei J, Pham HQH, Tao X, Guo J, Wang Z, Shen B, Su R, He C, Yang Y. EMBO Rep. 2025 Nov;26(22):5483-5500. doi: 10.1038/s44319-025-00590-7. Epub 2025 Oct 6. PubMed

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