Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

mCh-Rab7A Citations (14)

Originally described in: ER Contact Sites Define the Position and Timing of Endosome Fission.
Rowland AA, Chitwood PJ, Phillips MJ, Voeltz GK Cell. 2014 Nov 20;159(5):1027-41. doi: 10.1016/j.cell.2014.10.023.
PubMed Journal

Articles Citing mCh-Rab7A

VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. Tabara LC, Escalante R. PLoS One. 2016 Nov 18;11(11):e0166499. doi: 10.1371/journal.pone.0166499. eCollection 2016. PubMed
Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology. Gowrishankar S, Wu Y, Ferguson SM. J Cell Biol. 2017 Oct 2;216(10):3291-3305. doi: 10.1083/jcb.201612148. Epub 2017 Aug 7. PubMed
Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. Wong YC, Ysselstein D, Krainc D. Nature. 2018 Feb 15;554(7692):382-386. doi: 10.1038/nature25486. Epub 2018 Jan 24. PubMed
Vacuole membrane protein 1 marks endoplasmic reticulum subdomains enriched in phospholipid synthesizing enzymes and is required for phosphoinositide distribution. Tabara LC, Vicente JJ, Biazik J, Eskelinen EL, Vincent O, Escalante R. Traffic. 2018 Aug;19(8):624-638. doi: 10.1111/tra.12581. Epub 2018 Jun 10. PubMed
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. Kumar N, Leonzino M, Hancock-Cerutti W, Horenkamp FA, Li P, Lees JA, Wheeler H, Reinisch KM, De Camilli P. J Cell Biol. 2018 Oct 1;217(10):3625-3639. doi: 10.1083/jcb.201807019. Epub 2018 Aug 9. PubMed

Associated Plasmids

Chemical genetic identification of GAK substrates reveals its role in regulating Na(+)/K(+)-ATPase. Lin AW, Gill KK, Castaneda MS, Matucci I, Eder N, Claxton S, Flynn H, Snijders AP, George R, Ultanir SK. Life Sci Alliance. 2018 Dec 31;1(6):e201800118. doi: 10.26508/lsa.201800118. eCollection 2018 Dec. PubMed
VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation. Munoz-Braceras S, Tornero-Ecija AR, Vincent O, Escalante R. Dis Model Mech. 2019 Feb 22;12(2). pii: dmm.036681. doi: 10.1242/dmm.036681. PubMed
Rab7 regulates primary cilia disassembly through cilia excision. Wang G, Hu HB, Chang Y, Huang Y, Song ZQ, Zhou SB, Chen L, Zhang YC, Wu M, Tu HQ, Yuan JF, Wang N, Pan X, Li AL, Zhou T, Zhang XM, He K, Li HY. J Cell Biol. 2019 Dec 2;218(12):4030-4041. doi: 10.1083/jcb.201811136. Epub 2019 Oct 16. PubMed
SKIP-HOPS recruits TBC1D15 for a Rab7-to-Arl8b identity switch to control late endosome transport. Jongsma ML, Bakker J, Cabukusta B, Liv N, van Elsland D, Fermie J, Akkermans JL, Kuijl C, van der Zanden SY, Janssen L, Hoogzaad D, van der Kant R, Wijdeven RH, Klumperman J, Berlin I, Neefjes J. EMBO J. 2020 Mar 16;39(6):e102301. doi: 10.15252/embj.2019102301. Epub 2020 Feb 21. PubMed
The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance. Khobrekar NV, Quintremil S, Dantas TJ, Vallee RB. Dev Cell. 2020 Apr 20;53(2):141-153.e4. doi: 10.1016/j.devcel.2020.03.011. Epub 2020 Apr 9. PubMed
Type I Phosphatidylinositol-4-Phosphate 5-Kinases alpha and gamma Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane. Gonzales B, de Rocquigny H, Beziau A, Durand S, Burlaud-Gaillard J, Lefebvre A, Krull S, Emond P, Brand D, Piver E. J Virol. 2020 Jul 1;94(14). pii: JVI.00189-20. doi: 10.1128/JVI.00189-20. Print 2020 Jul 1. PubMed
Overexpressed coiled-coil domain containing protein 8 (CCDC8) mediates newly synthesized HIV-1 Gag lysosomal degradation. Jiang X, Jia X, Sun J, Qi C, Lu L, Wang Y, Zhang L, Wei M. Sci Rep. 2020 Jul 10;10(1):11416. doi: 10.1038/s41598-020-68341-3. PubMed
The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7. Trofimenko E, Homma Y, Fukuda M, Widmann C. Cell Rep. 2021 Nov 2;37(5):109945. doi: 10.1016/j.celrep.2021.109945. PubMed
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling. Hancock-Cerutti W, Wu Z, Xu P, Yadavalli N, Leonzino M, Tharkeshwar AK, Ferguson SM, Shadel GS, De Camilli P. J Cell Biol. 2022 Jul 4;221(7):e202106046. doi: 10.1083/jcb.202106046. Epub 2022 Jun 3. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.