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SP-Cas9 Citations (14)

Originally described in: Efficient Intracellular Delivery of Native Proteins.
D'Astolfo DS, Pagliero RJ, Pras A, Karthaus WR, Clevers H, Prasad V, Lebbink RJ, Rehmann H, Geijsen N Cell. 2015 Apr 23;161(3):674-690. doi: 10.1016/j.cell.2015.03.028.
PubMed Journal

Articles Citing SP-Cas9

Articles
Increasing Cas9-mediated homology-directed repair efficiency through covalent tethering of DNA repair template. Aird EJ, Lovendahl KN, St Martin A, Harris RS, Gordon WR. Commun Biol. 2018 May 31;1:54. doi: 10.1038/s42003-018-0054-2. eCollection 2018. PubMed

Associated Plasmids

Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain. Kuil LE, Oosterhof N, Geurts SN, van der Linde HC, Meijering E, van Ham TJ. Dis Model Mech. 2019 Mar 8;12(3). pii: dmm.037762. doi: 10.1242/dmm.037762. PubMed
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions. Akula MK, Ibrahim MX, Ivarsson EG, Khan OM, Kumar IT, Erlandsson M, Karlsson C, Xu X, Brisslert M, Brakebusch C, Wang D, Bokarewa M, Sayin VI, Bergo MO. Nat Commun. 2019 Sep 4;10(1):3975. doi: 10.1038/s41467-019-11606-x. PubMed
The dystonia gene THAP1 controls DNA double-strand break repair choice. Shinoda K, Zong D, Callen E, Wu W, Dumitrache LC, Belinky F, Chari R, Wong N, Ishikawa M, Stanlie A, Multhaupt-Buell T, Sharma N, Ozelius L, Ehrlich M, McKinnon PJ, Nussenzweig A. Mol Cell. 2021 Jun 17;81(12):2611-2624.e10. doi: 10.1016/j.molcel.2021.03.034. Epub 2021 Apr 14. PubMed
Bi-allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis-like disease. Sofou K, Meier K, Sanderson LE, Kaminski D, Montoliu-Gaya L, Samuelsson E, Blomqvist M, Agholme L, Gartner J, Muhlhausen C, Darin N, Barakat TS, Schlotawa L, van Ham T, Asin Cayuela J, Sterky FH. EMBO Mol Med. 2021 May 7;13(5):e13376. doi: 10.15252/emmm.202013376. Epub 2021 May 3. PubMed
Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development. Kuil LE, MacKenzie KC, Tang CS, Windster JD, Le TL, Karim A, de Graaf BM, van der Helm R, van Bever Y, Sloots CEJ, Meeussen C, Tibboel D, de Klein A, Wijnen RMH, Amiel J, Lyonnet S, Garcia-Barcelo MM, Tam PKH, Alves MM, Brooks AS, Hofstra RMW, Brosens E. PLoS Genet. 2021 Aug 6;17(8):e1009698. doi: 10.1371/journal.pgen.1009698. eCollection 2021 Aug. PubMed
Impact of Formulation Conditions on Lipid Nanoparticle Characteristics and Functional Delivery of CRISPR RNP for Gene Knock-Out and Correction. Walther J, Wilbie D, Tissingh VSJ, Oktem M, van der Veen H, Lou B, Mastrobattista E. Pharmaceutics. 2022 Jan 17;14(1):213. doi: 10.3390/pharmaceutics14010213. PubMed
Engineering T-Cell Resistance to HIV-1 Infection via Knock-In of Peptides from the Heptad Repeat 2 Domain of gp41. Maslennikova A, Kruglova N, Kalinichenko S, Komkov D, Shepelev M, Golubev D, Siniavin A, Vzorov A, Filatov A, Mazurov D. mBio. 2022 Jan 25:e0358921. doi: 10.1128/mbio.03589-21. PubMed

Associated Plasmids

Ligation-assisted homologous recombination enables precise genome editing by deploying both MMEJ and HDR. Zhao Z, Shang P, Sage F, Geijsen N. Nucleic Acids Res. 2022 Jun 24;50(11):e62. doi: 10.1093/nar/gkac118. PubMed
Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis. Bomfim CCB, Fisher L, Amaral EP, Mittereder L, McCann K, Correa AAS, Namasivayam S, Swamydas M, Moayeri M, Weiss JM, Chari R, McVicar DW, Costa DL, D'Imperio Lima MR, Sher A. Front Cell Infect Microbiol. 2022 May 2;12:862582. doi: 10.3389/fcimb.2022.862582. eCollection 2022. PubMed
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy. Berdowski WM, van der Linde HC, Breur M, Oosterhof N, Beerepoot S, Sanderson L, Wijnands LI, de Jong P, Tsai-Meu-Chong E, de Valk W, de Witte M, van IJcken WFJ, Demmers J, van der Knaap MS, Bugiani M, Wolf NI, van Ham TJ. Acta Neuropathol. 2022 Aug;144(2):211-239. doi: 10.1007/s00401-022-02440-5. Epub 2022 Jun 17. PubMed
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment. Smits DJ, Dekker J, Schot R, Tabarki B, Alhashem A, Demmers JAA, Dekkers DHW, Romito A, van der Spek PJ, van Ham TJ, Bertoli-Avella AM, Mancini GMS. Hum Genet. 2023 Mar;142(3):379-397. doi: 10.1007/s00439-022-02511-3. Epub 2022 Dec 20. PubMed
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Chakraborty S, Kopitchinski N, Zuo Z, Eraso A, Awasthi P, Chari R, Mitra A, Tobias IC, Moorthy SD, Dale RK, Mitchell JA, Petros TJ, Rocha PP. Nat Genet. 2023 Feb;55(2):280-290. doi: 10.1038/s41588-022-01295-6. Epub 2023 Jan 30. PubMed
Efficient Editing of the CXCR4 Locus Using Cas9 Ribonucleoprotein Complexes Stabilized with Polyglutamic Acid. Golubev DS, Komkov DS, Shepelev MV, Mazurov DV, Kruglova NA. Dokl Biol Sci. 2024 Jan 8. doi: 10.1134/S0012496623700862. PubMed

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