Gal4-VP16 Citations (16)
Originally described in: Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation.Budzynski MA, Puustinen MC, Joutsen J, Sistonen L Mol Cell Biol. 2015 Jul;35(14):2530-40. doi: 10.1128/MCB.00816-14. Epub 2015 May 11. PubMed Journal
Articles Citing Gal4-VP16
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| Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos. Koromila T, Gao F, Iwasaki Y, He P, Pachter L, Gergen JP, Stathopoulos A. Elife. 2020 Jul 23;9. pii: 59610. doi: 10.7554/eLife.59610. PubMed |
| Chemical Starting Matter for HNF4alpha Ligand Discovery and Chemogenomics. Meijer I, Willems S, Ni X, Heering J, Chaikuad A, Merk D. Int J Mol Sci. 2020 Oct 24;21(21). pii: ijms21217895. doi: 10.3390/ijms21217895. PubMed |
| Fragment-like Chloroquinolineamines Activate the Orphan Nuclear Receptor Nurr1 and Elucidate Activation Mechanisms. Willems S, Ohrndorf J, Kilu W, Heering J, Merk D. J Med Chem. 2021 Mar 11;64(5):2659-2668. doi: 10.1021/acs.jmedchem.0c01779. Epub 2021 Feb 25. PubMed |
| The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines. Faudone G, Kilu W, Ni X, Chaikuad A, Sreeramulu S, Heitel P, Schwalbe H, Knapp S, Schubert-Zsilavecz M, Heering J, Merk D. ACS Pharmacol Transl Sci. 2021 Nov 23;4(6):1794-1807. doi: 10.1021/acsptsci.1c00195. eCollection 2021 Dec 10. PubMed |
| Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries. Willems S, Muller M, Ohrndorf J, Heering J, Proschak E, Merk D. ChemMedChem. 2022 Apr 20;17(8):e202200026. doi: 10.1002/cmdc.202200026. Epub 2022 Feb 21. PubMed |
| Nurr1 Modulation Mediates Neuroprotective Effects of Statins. Willems S, Marschner JA, Kilu W, Faudone G, Busch R, Duensing-Kropp S, Heering J, Merk D. Adv Sci (Weinh). 2022 Jun;9(18):e2104640. doi: 10.1002/advs.202104640. Epub 2022 Apr 30. PubMed |
| Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR-1) Reveals Inverse NOR-1 Agonists. Zaienne D, Arifi S, Marschner JA, Heering J, Merk D. ChemMedChem. 2022 Aug 17;17(16):e202200259. doi: 10.1002/cmdc.202200259. Epub 2022 Jul 7. PubMed |
| Development of a Potent Nurr1 Agonist Tool for In Vivo Applications. Vietor J, Gege C, Stiller T, Busch R, Schallmayer E, Kohlhof H, Hofner G, Pabel J, Marschner JA, Merk D. J Med Chem. 2023 May 11;66(9):6391-6402. doi: 10.1021/acs.jmedchem.3c00415. Epub 2023 Apr 26. PubMed |
| Genetic Silencing of AKT Induces Melanoma Cell Death via mTOR Suppression. Parkman GL, Turapov T, Kircher DA, Burnett WJ, Stehn CM, O'Toole K, Culver KM, Chadwick AT, Elmer RC, Flaherty R, Stanley KA, Foth M, Lum DH, Judson-Torres RL, Friend JE, VanBrocklin MW, McMahon M, Holmen SL. Mol Cancer Ther. 2024 Mar 4;23(3):301-315. doi: 10.1158/1535-7163.MCT-23-0474. PubMed |
| Chemogenomics for NR1 nuclear hormone receptors. Isigkeit L, Schallmayer E, Busch R, Brunello L, Menge A, Elson L, Muller S, Knapp S, Stolz A, Marschner JA, Merk D. Nat Commun. 2024 Jun 18;15(1):5201. doi: 10.1038/s41467-024-49493-6. PubMed |
Destabilized near-infrared fluorescent nanobodies enable background-free targeting of GFP-based biosensors for imaging and manipulation.
Barykina NV, Carey EM, Oliinyk OS, Nimmerjahn A, Verkhusha VV.
Nat Commun. 2024 Sep 6;15(1):7788. doi: 10.1038/s41467-024-51857-x.
PubMed
Associated Plasmids |
| Efficient suppression of premature termination codons with alanine by engineered chimeric pyrrolysine tRNAs. Awawdeh A, Tapia A, Alshawi SA, Dawodu O, Gaier SA, Specht C, Beaudoin JD, Tharp JM, Vargas-Rodriguez O. Nucleic Acids Res. 2024 Dec 11;52(22):14244-14259. doi: 10.1093/nar/gkae1048. PubMed |
| Chemogenomics for steroid hormone receptors (NR3). Schallmayer E, Isigkeit L, Elson L, Muller S, Knapp S, Marschner JA, Merk D. Commun Chem. 2025 Feb 3;8(1):29. doi: 10.1038/s42004-025-01427-z. PubMed |
| An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations. Specht C, Tapia A, Penrod S, Soriano GA, Awawdeh A, Alshawi SA, White CA, Beaudoin JD, Doud EH, Vargas-Rodriguez O, Huang Y, Tharp JM. Nucleic Acids Res. 2025 Jun 20;53(12):gkaf532. doi: 10.1093/nar/gkaf532. PubMed |
| Comparative Profiling and Chemogenomics Application of Chemical Tools for NR4A Nuclear Receptors. Willems S, Morozov V, Marschner JA, Merk D. J Med Chem. 2025 Oct 9;68(19):19955-19970. doi: 10.1021/acs.jmedchem.5c00459. Epub 2025 Sep 18. PubMed |
| Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators. Bandomir NC, Hormann T, Karcher A, Kaiser A, Merk D, Heitel P. J Med Chem. 2025 Nov 13;68(21):22588-22598. doi: 10.1021/acs.jmedchem.5c01551. Epub 2025 Oct 23. PubMed |
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