pcDNA3-N-Flag-ASC1 Citations (9)

Originally described in: NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, Arnett S, Jurek P, Chen D, Kravchenko VV, Mathison JC, Moresco EM, Monson NL, Ulevitch RJ, Beutler B Nat Immunol. 2016 Mar;17(3):250-8. doi: 10.1038/ni.3333. Epub 2015 Dec 7. PubMed Journal

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Articles Citing pcDNA3-N-Flag-ASC1

Articles
Reconstruction of the Mouse Inflammasome System in HEK293T Cells. Shi H, Murray A, Beutler B. Bio Protoc. 2016 Nov 5;6(21). pii: e1986. doi: 10.21769/BioProtoc.1986. PubMed
Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM. Carty M, Kearney J, Shanahan KA, Hams E, Sugisawa R, Connolly D, Doran CG, Munoz-Wolf N, Gurtler C, Fitzgerald KA, Lavelle EC, Fallon PG, Bowie AG. Immunity. 2019 Jun 18;50(6):1412-1424.e6. doi: 10.1016/j.immuni.2019.04.005. Epub 2019 May 7. PubMed
Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination. Zhang L, Ko CJ, Li Y, Jie Z, Zhu L, Zhou X, Xie X, Gao T, Liu T, Cheng X, Sun SC. Cell Rep. 2021 Oct 26;37(4):109904. doi: 10.1016/j.celrep.2021.109904. PubMed
Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages. Zhu L, Qi W, Yang G, Yang Y, Wang Y, Zheng L, Fu Y, Cheng X. Cells. 2022 May 12;11(10). pii: cells11101630. doi: 10.3390/cells11101630. PubMed
Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity. Feriotti C, Sa-Pessoa J, Calderon-Gonzalez R, Gu L, Morris B, Sugisawa R, Insua JL, Carty M, Dumigan A, Ingram RJ, Kissenpfening A, Bowie AG, Bengoechea JA. Cell Rep. 2022 Aug 9;40(6):111167. doi: 10.1016/j.celrep.2022.111167. PubMed
SARS-COV-2 viroporins activate the NLRP3-inflammasome by the mitochondrial permeability transition pore. Guarnieri JW, Angelin A, Murdock DG, Schaefer P, Portluri P, Lie T, Huang J, Wallace DC. Front Immunol. 2023 Feb 20;14:1064293. doi: 10.3389/fimmu.2023.1064293. eCollection 2023. PubMed
Inherently Reduced Expression of ASC Restricts Caspase-1 Processing in Hepatocytes and Promotes Plasmodium Infection. Marques-da-Silva C, Schmidt-Silva C, Baptista RP, Kurup SP. J Immunol. 2024 Feb 15;212(4):596-606. doi: 10.4049/jimmunol.2300440. PubMed
A cytomegalovirus inflammasome inhibitor reduces proinflammatory cytokine release and pyroptosis. Deng Y, Ostermann E, Brune W. Nat Commun. 2024 Jan 26;15(1):786. doi: 10.1038/s41467-024-45151-z. PubMed
Fungal Als proteins hijack host death effector domains to promote inflammasome signaling. Zhou T, Solis NV, Marshall M, Yao Q, Pearlman E, Filler SG, Liu H. Nat Commun. 2025 Feb 12;16(1):1562. doi: 10.1038/s41467-025-56657-5. PubMed

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