pGEX-4T1 SHP2 WT Citations (5)

Originally described in: Activated mutants of SHP-2 preferentially induce elongation of Xenopus animal caps.
O'Reilly AM, Pluskey S, Shoelson SE, Neel BG Mol Cell Biol 2000 Jan;20(1):299-311. PubMed Journal

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Articles Citing pGEX-4T1 SHP2 WT

Articles
Molecular mechanism of interleukin-2-induced mucosal homeostasis. Mishra J, Waters CM, Kumar N. Am J Physiol Cell Physiol. 2012 Mar 1;302(5):C735-47. doi: 10.1152/ajpcell.00316.2011. Epub 2011 Nov 23. PubMed
Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Guo W, Liu W, Chen Z, Gu Y, Peng S, Shen L, Shen Y, Wang X, Feng GS, Sun Y, Xu Q. Nat Commun. 2017 Dec 18;8(1):2168. doi: 10.1038/s41467-017-02351-0. PubMed
The pathogenic T42A mutation in SHP2 rewires interaction specificity and enhances signaling. van Vlimmeren AE, Voleti R, Chartier CA, Jiang Z, Karandur D, Shah NH. bioRxiv. 2023 Jul 30:2023.07.10.548257. doi: 10.1101/2023.07.10.548257. Preprint. PubMed
The Toxoplasma secreted effector TgWIP modulates dendritic cell motility by activating host tyrosine phosphatases Shp1 and Shp2. Morales P, Brown AJ, Sangare LO, Yang S, Kuihon SVNP, Chen B, Saeij JPJ. Cell Mol Life Sci. 2024 Jul 9;81(1):294. doi: 10.1007/s00018-024-05283-3. PubMed
Ionizable networks mediate pH-dependent allostery in SH2 signaling proteins. Van Dyck PK, Piszkin L, Gorski EA, Nascimento ET, Abebe JA, Hoffmann LM, Peng JW, White KA. bioRxiv [Preprint]. 2024 Aug 21:2024.08.21.608875. doi: 10.1101/2024.08.21.608875. PubMed

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