pRK5-HA-KPTN Citations (3)

Originally described in: KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM Nature. 2017 Feb 15. doi: 10.1038/nature21423. PubMed Journal

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Articles Citing pRK5-HA-KPTN

Articles
CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth. Yin S, Liu L, Ball LE, Wang Y, Bedford MT, Duncan SA, Wang H, Gan W. Cell Rep. 2023 Apr 25;42(4):112316. doi: 10.1016/j.celrep.2023.112316. Epub 2023 Mar 29. PubMed
E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro. Lear TB, Boudreau AN, Lockwood KC, Chu E, Camarco DP, Cao Q, Nguyen M, Evankovich JW, Finkel T, Liu Y, Chen BB. J Biol Chem. 2023 Dec;299(12):105388. doi: 10.1016/j.jbc.2023.105388. Epub 2023 Oct 27. PubMed
Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex. Lupton CJ, Bayly-Jones C, Dong S, Lam T, Luo W, Jones GD, Mastos C, Frescher NJ, Lim SS, Keen AC, Formosa LE, Venugopal H, Chang YG, Halls ML, Ellisdon AM. Cell. 2026 Feb 19;189(4):1185-1200.e28. doi: 10.1016/j.cell.2025.12.005. Epub 2026 Jan 8. PubMed

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