pCMV4-ApoE4 Citations (4)

Originally described in: Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.
Hudry E, Dashkoff J, Roe AD, Takeda S, Koffie RM, Hashimoto T, Scheel M, Spires-Jones T, Arbel-Ornath M, Betensky R, Davidson BL, Hyman BT Sci Transl Med. 2013 Nov 20;5(212):212ra161. doi: 10.1126/scitranslmed.3007000. PubMed Journal

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Articles Citing pCMV4-ApoE4

Articles
Human ApoE2 Endows Stronger Contractility in Rat Cardiomyocytes Enhancing Heart Function. Wu Y, Zhao F, Sure VN, Ibrahim A, Yu C, Carr SM, Song P. Cells. 2023 Jan 17;12(3):347. doi: 10.3390/cells12030347. PubMed
Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis. Adaku N, Ostendorf BN, Mei W, Tavazoie SF. Cancer Res. 2023 Sep 15;83(18):3013-3025. doi: 10.1158/0008-5472.CAN-23-1252. PubMed
Apolipoprotein E epsilon4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCepsilon mislocalization in cholinergic neuronal cells. Piccarducci R, Giacomelli C, Bertilacchi MS, Benito-Martinez A, Di Giorgi N, Daniele S, Signore G, Rocchiccioli S, Vilar M, Marchetti L, Martini C. Biochim Biophys Acta Mol Basis Dis. 2023 Oct;1869(7):166793. doi: 10.1016/j.bbadis.2023.166793. Epub 2023 Jun 17. PubMed
APOE4 impairs autophagy and Abeta clearance by microglial cells. Bassal R, Rivkin-Natan M, Rabinovich A, Michaelson DM, Frenkel D, Pinkas-Kramarski R. Inflamm Res. 2025 Apr 1;74(1):61. doi: 10.1007/s00011-025-02016-5. PubMed

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