pCDNA5-Flag-BRD4-BD Citations (4)

Originally described in: Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Huh SJ, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, Peluffo G, Brown J, D'Santos C, Krop IE, Dillon D, McKeown M, Ott C, Qi J, Ni M, Rao PK, Duarte M, Wu SY, Chiang CM, Anders L, Young RA, Winer EP, Letai A, Barry WT, Carroll JS, Long HW, Brown M, Liu XS, Meyer CA, Bradner JE, Polyak K Nature. 2016 Jan 21;529(7586):413-7. doi: 10.1038/nature16508. Epub 2016 Jan 6. PubMed Journal

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Articles Citing pCDNA5-Flag-BRD4-BD

Articles
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4. Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S. Nat Med. 2018 Oct;24(10):1599-1610. doi: 10.1038/s41591-018-0158-8. Epub 2018 Sep 17. PubMed
Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity. Zhang S, Roeder RG. Nat Struct Mol Biol. 2025 Jan;32(1):98-112. doi: 10.1038/s41594-024-01384-6. Epub 2024 Sep 9. PubMed
BET degraders reveal BRD4 disruption of 7SK and P-TEFb is critical for effective reactivation of latent HIV in CD4+ T-cells. Turner A-MW, Bashore FM, Falcinelli SD, Fox JA, Keller AL, Fenton AD, Geyer RF, Allard B, Kirchherr JL, Archin NM, James LI, Margolis DM. J Virol. 2025 Apr 15;99(4):e0177724. doi: 10.1128/jvi.01777-24. Epub 2025 Mar 11. PubMed
Depletion of BRD9-mediated R-loop accumulation inhibits leukemia cell growth via transcription-replication conflict. Lee SY, Lee SH, Kwak MJ, Kim JY, Perren JO, Miller KM, Kim JJ. Nucleic Acids Res. 2025 Jun 20;53(12):gkaf613. doi: 10.1093/nar/gkaf613. PubMed

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