TDP-43_CTD Citations (8)

Originally described in: ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Conicella AE, Zerze GH, Mittal J, Fawzi NL Structure. 2016 Sep 6;24(9):1537-49. doi: 10.1016/j.str.2016.07.007. Epub 2016 Aug 18. PubMed Journal

---

Articles Citing TDP-43_CTD

Articles
Granulins modulate liquid-liquid phase separation and aggregation of the prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43. Bhopatkar AA, Uversky VN, Rangachari V. J Biol Chem. 2020 Feb 21;295(8):2506-2519. doi: 10.1074/jbc.RA119.011501. Epub 2020 Jan 6. PubMed
NMR assignments for the C-terminal domain of human TDP-43. Pantoja-Uceda D, Stuani C, Laurents DV, McDermott AE, Buratti E, Mompean M. Biomol NMR Assign. 2021 Apr;15(1):177-181. doi: 10.1007/s12104-020-10002-7. Epub 2021 Jan 8. PubMed
Tryptophan Probes of TDP-43 C-Terminal Domain Amyloid Formation. Shuster SO, Lee JC. J Phys Chem B. 2021 Apr 22;125(15):3781-3789. doi: 10.1021/acs.jpcb.1c00767. Epub 2021 Apr 9. PubMed
Phe-Gly motifs drive fibrillization of TDP-43's prion-like domain condensates. Pantoja-Uceda D, Stuani C, Laurents DV, McDermott AE, Buratti E, Mompean M. PLoS Biol. 2021 Apr 28;19(4):e3001198. doi: 10.1371/journal.pbio.3001198. eCollection 2021 Apr. PubMed
Liquid-Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation. Pakravan D, Michiels E, Bratek-Skicki A, De Decker M, Van Lindt J, Alsteens D, Derclaye S, Van Damme P, Schymkowitz J, Rousseau F, Tompa P, Van Den Bosch L. Biomolecules. 2021 Apr 8;11(4). pii: biom11040548. doi: 10.3390/biom11040548. PubMed
Watching liquid droplets of TDP-43CTD age by Raman spectroscopy. Shuster SO, Lee JC. J Biol Chem. 2022 Feb;298(2):101528. doi: 10.1016/j.jbc.2021.101528. Epub 2021 Dec 23. PubMed
Charge and redox states modulate granulin-TDP-43 coacervation toward phase separation or aggregation. Bhopatkar AA, Dhakal S, Abernathy HG, Morgan SE, Rangachari V. Biophys J. 2022 Jun 7;121(11):2107-2126. doi: 10.1016/j.bpj.2022.04.034. Epub 2022 Apr 30. PubMed
TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43. Rummens J, Khalil B, Yildirim G, Silva P, Zorzini V, Peredo N, Wojno M, Ramakers M, Van Den Bosch L, Van Damme P, Davie K, Hendrix J, Rousseau F, Schymkowitz J, Da Cruz S. Neuron. 2025 May 21;113(10):1597-1613.e8. doi: 10.1016/j.neuron.2025.03.004. Epub 2025 Mar 28. PubMed

If you have published an article using this material, please email us at to have your article added to this page.