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Christian Stehlik Lab Plasmids


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Title Authors Publication
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. Bryan NB, Dorfleutner A, Rojanasakul Y, Stehlik C J Immunol. 2009 Mar 1;182(5):3173-82. doi: 10.4049/jimmunol.0802367.
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Khare S, Dorfleutner A, Bryan NB, Yun C, Radian AD, de Almeida L, Rojanasakul Y, Stehlik C Immunity. 2012 Mar 23;36(3):464-76. doi: 10.1016/j.immuni.2012.02.001. Epub 2012 Feb 21.
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Dorfleutner A, Bryan NB, Talbott SJ, Funya KN, Rellick SL, Reed JC, Shi X, Rojanasakul Y, Flynn DC, Stehlik C Infect Immun. 2007 Mar;75(3):1484-92. Epub 2006 Dec 18.
The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. de Almeida L, Khare S, Misharin AV, Patel R, Ratsimandresy RA, Wallin MC, Perlman H, Greaves DR, Hoffman HM, Dorfleutner A, Stehlik C Immunity. 2015 Aug 18;43(2):264-76. doi: 10.1016/j.immuni.2015.07.018. Epub 2015 Aug 11.
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses. Khare S, Ratsimandresy RA, de Almeida L, Cuda CM, Rellick SL, Misharin AV, Wallin MC, Gangopadhyay A, Forte E, Gottwein E, Perlman H, Reed JC, Greaves DR, Dorfleutner A, Stehlik C Nat Immunol. 2014 Apr;15(4):343-53. doi: 10.1038/ni.2829. Epub 2014 Feb 16.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
73952pcDNA3-Myc-ASCPYD and CARD domain containing, PYCARD (Homo sapiens)Mammalian ExpressionActivation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. J Immunol. 2009 Mar 1;182(5):3173-82. doi: 10.4049/jimmunol.0802367. Express c-Myc-tagged human ASC in mammalian cells pcDNA3 PYCARD ASC, CARD5, TMS, TMS-1, TMS1 Add to Cart
73953pCMV-pro-IL1binterleukin-1 beta (Mus musculus)Mammalian ExpressionActivation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. J Immunol. 2009 Mar 1;182(5):3173-82. doi: 10.4049/jimmunol.0802367. Express murine pro-interleukin-1 beta in mammalian cells pCMV or pcDNA3 Il1b IL-1beta, Il-1b Add to Cart
73955pEGFP-C2-NLRP3NLR family, pyrin domain containing 3 (NLRP3) (Homo sapiens)Mammalian ExpressionAn NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity. 2012 Mar 23;36(3):464-76. doi: 10.1016/j.immuni.2012.02.001. Epub 2012 Feb 21. Express EGFP-tagged human NLRP3 in mammalian cells pEGFP-C2 NLRP3 AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCAS1, FCU, MWS, NALP3, PYPAF1 Add to Cart
73956pcDNA3-Myc-NLRP3(R260W)NLR family, pyrin domain containing 3 (NLRP3) (Homo sapiens)Mammalian ExpressionCellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Infect Immun. 2007 Mar;75(3):1484-92. Epub 2006 Dec 18. Express c-Myc-tagged human NLRP3(R260W) in mammalian cells pcDNA3 NLRP3 AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCAS1, FCU, MWS, NALP3, PYPAF1 Add to Cart
73957pLEX-MCS-ASC-GFPPYD and CARD domain containing, PYCARD (Homo sapiens)Mammalian Expression, LentiviralThe PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity. 2015 Aug 18;43(2):264-76. doi: 10.1016/j.immuni.2015.07.018. Epub 2015 Aug 11. Express human ASC with a C-terminal EGFP tag in mammalian cells pLEX-Myc PYCARD ASC, CARD5, TMS, TMS-1, TMS1 Add to Cart
73958pcDNA3-Myc-AIM2absent in melanoma 2 (AIM2) (Homo sapiens)Mammalian ExpressionThe PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses. Nat Immunol. 2014 Apr;15(4):343-53. doi: 10.1038/ni.2829. Epub 2014 Feb 16. Express c-Myc-tagged human AIM2 in mammalian cells pcDNA3 AIM2 PYHIN4 Add to Cart