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L. Miguel Martins Lab Plasmids


The L. Miguel Martins Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving life science research.

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Title Authors Publication
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. Martins LM, Iaccarino I, Tenev T, Gschmeissner S, Totty NF, Lemoine NR, Savopoulos J, Gray CW, Creasy CL, Dingwall C, Downward J J Biol Chem. 2002 Jan 4. 277(1):439-44.
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells. Nicke B, Bastien J, Khanna SJ, Warne PH, Cowling V, Cook SJ, Peters G, Delpuech O, Schulze A, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Ganesan TS, Downward J, Hancock DC Mol Cell. 2005 Dec 9. 20(5):673-85.
Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi. Martins LM, Turk BE, Cowling V, Borg A, Jarrell ET, Cantley LC, Downward J J Biol Chem. 2003 Dec 5. 278(49):49417-27.
pBabe-IRES-EGFP plasmids (unpublished)
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Plun-Favreau H, Klupsch K, Moisoi N, Gandhi S, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N, Wood NW, Martins LM, Downward J Nat Cell Biol. 2007 Sep 30. ():.
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D, Gasser T, Wszolek Z, Muller T, Bornemann A, Wolburg H, Downward J, Riess O, Schulz JB, Kruger R Hum Mol Genet. 2005 Aug 1. 14(15):2099-111.
MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins. Lam D, Dickens D, Reid EB, Loh SH, Moisoi N, Martins LM Proc Natl Acad Sci U S A. 2009 Jul 8. ():.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
14121pcDNA3-HtrA2-EGFPHtrA2 (Homo sapiens)Mammalian ExpressionThe serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J Biol Chem. 2002 Jan 4. 277(1):439-44. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
14122pcDNA3-HtrA2-EGFP S306AHtrA2 (Homo sapiens)Mammalian ExpressionThe serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J Biol Chem. 2002 Jan 4. 277(1):439-44. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
14123pcDNA3-delta33HtrA-EGFP S306AHtrA2 (Homo sapiens)Mammalian ExpressionThe serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J Biol Chem. 2002 Jan 4. 277(1):439-44. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
14124pcDNA3-delta133HtrA-EGFPHtrA2 (Homo sapiens)Mammalian ExpressionThe serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J Biol Chem. 2002 Jan 4. 277(1):439-44. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
14125pMig (Martins Lab)IRES-EGFPMammalian Expression, Retroviral, RNAiInvolvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells. Mol Cell. 2005 Dec 9. 20(5):673-85. pRetroSuper Add to Cart
14126pET20b-delta133HtrA2HtrA2 (Homo sapiens)Bacterial ExpressionBinding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi. J Biol Chem. 2003 Dec 5. 278(49):49417-27. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
14430pBabe puro IRES-EGFPIRES-EGFPMammalian Expression, Retroviral pBabe-IRES-EGFP plasmids (unpublished) pBabe puro Add to Cart
14431pBabe neo IRES-EGFPIRES-EGFPMammalian Expression, Retroviral pBabe-IRES-EGFP plasmids (unpublished) pBabe neo Add to Cart
14432pBabe bleo IRES-EGFPIRES-EGFPMammalian Expression, Retroviral pBabe-IRES-EGFP plasmids (unpublished) pBabe bleo Add to Cart
15938pcDNA3-HtrA2-FLAGHtrA2 (Homo sapiens)Mammalian ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
15939pcDNA3-HtrA2-FLAG S142DHtrA2 (Homo sapiens)Mammalian ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
15940pcDNA3-HtrA2-FLAG S400DHtrA2 (Homo sapiens)Mammalian ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pcDNA3 HTRA2 OMI, PARK13, PRSS25 Add to Cart
16153pET20b-delta133HtrA2 S142AHtrA2 (Homo sapiens)Bacterial ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
16154pET20b-delta133HtrA2 S142DHtrA2 (Homo sapiens)Bacterial ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
16155pET20b-delta133HtrA2 S400AHtrA2 (Homo sapiens)Bacterial ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
16156pET20b-delta133HtrA2 S400DHtrA2 (Homo sapiens)Bacterial ExpressionThe mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol. 2007 Sep 30. ():. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
16157pET20b-delta133HtrA2 A141SHtrA2 (Homo sapiens)Bacterial ExpressionLoss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet. 2005 Aug 1. 14(15):2099-111. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
16158pET20b-delta133HtrA2 G399SHtrA2 (Homo sapiens)Bacterial ExpressionLoss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet. 2005 Aug 1. 14(15):2099-111. pET20b HTRA2 OMI, PARK13, PRSS25 Add to Cart
16207pGEX2TK-PDZ(HtrA2)HtrA2 (Homo sapiens)Bacterial ExpressionBinding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi. J Biol Chem. 2003 Dec 5. 278(49):49417-27. pGEX-2TK HTRA2 OMI, PARK13, PRSS25 Add to Cart
21731MAP4K3-GFPMAP4K3 (Homo sapiens)Mammalian ExpressionMAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins. Proc Natl Acad Sci U S A. 2009 Jul 8. ():. pcDNA3.1/CT-GFP-TOPO MAP4K3 GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1 Add to Cart
21732MAP4K3-GFP d344-873MAP4K3 (Homo sapiens)Mammalian ExpressionMAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins. Proc Natl Acad Sci U S A. 2009 Jul 8. ():. pEGFP-N1 MAP4K3 GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1 Add to Cart
21733MAP4K3-GFP d1-343MAP4K3 (Homo sapiens)Mammalian ExpressionMAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins. Proc Natl Acad Sci U S A. 2009 Jul 8. ():. pEGFP-N1 MAP4K3 GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1 Add to Cart
21734MAP4K3-GFP K45EMAP4K3 (Homo sapiens)Mammalian ExpressionMAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins. Proc Natl Acad Sci U S A. 2009 Jul 8. ():. pcDNA3.1/CT-GFP-TOPO MAP4K3 GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1 Add to Cart
21735MAP4K3-GFP d344-873, K45EMAP4K3 (Homo sapiens)Mammalian ExpressionMAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins. Proc Natl Acad Sci U S A. 2009 Jul 8. ():. pEGFP-N1 MAP4K3 GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1 Add to Cart