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Robert Bradley Lab Plasmids


The Robert Bradley Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving life science research.

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Title Authors Publication
SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Kim E, Ilagan JO, Liang Y, Daubner GM, Lee SC, Ramakrishnan A, Li Y, Chung YR, Micol JB, Murphy ME, Cho H, Kim MK, Zebari AS, Aumann S, Park CY, Buonamici S, Smith PG, Deeg HJ, Lobry C, Aifantis I, Modis Y, Allain FH, Halene S, Bradley RK, Abdel-Wahab O Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006.
U2AF1 mutations alter splice site recognition in hematological malignancies. Ilagan JO, Ramakrishnan A, Hayes B, Murphy ME, Zebari AS, Bradley P, Bradley RK Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29.
A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy. Feng Q, Snider L, Jagannathan S, Tawil R, van der Maarel SM, Tapscott SJ, Bradley RK Elife. 2015 Jan 7;4. doi: 10.7554/eLife.04996.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
83967pRKB133_GI-DUX4-intron2(+)DUX4-3'UTR-intron2(+) (Homo sapiens)Mammalian ExpressionA feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy. Elife. 2015 Jan 7;4. doi: 10.7554/eLife.04996. to test DUX4 mRNA is subjected to NMD upon intron2 inclusion β-globin NMD reporter wild-type DUX4 DUX4L Add to Cart
83968pRKB134_GI-DUX4-intron2(-)DUX4-3'UTR-intron2(-) (Homo sapiens)Mammalian ExpressionA feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy. Elife. 2015 Jan 7;4. doi: 10.7554/eLife.04996. to test DUX4 mRNA is subjected to NMD upon intron2 inclusion β-globin NMD reporter wild-type DUX4 DUX4L Add to Cart
84014pUB6_EZH2EZH2 (Homo sapiens)Mammalian ExpressionSRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006. EZH2 minigene to test splicing event pUB6/V5-HisA EZH2 ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2 Add to Cart
84015pUB6_EPB49EPB49 (Homo sapiens)Mammalian ExpressionU2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29. EPB49 minigene to test splicing event pUB6/V5-HisA DMTN DMT, EPB49 Add to Cart
84016pUB6_ATRATR (Homo sapiens)Mammalian ExpressionU2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29. ATR minigene to test splicing event pUB6/V5-HisA ATR FCTCS, FRP1, MEC1, SCKL, SCKL1 Add to Cart
84017pRRL_U2AF1_WT_mCherryU2AF1 (Homo sapiens)Mammalian Expression, LentiviralU2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29. expression of U2AF1 in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE U2AF1 FP793, RN, RNU2AF1, U2AF35, U2AFBP Add to Cart
84018pRRL_U2AF1_S34Y_mCherryU2AF1 (Homo sapiens)Mammalian Expression, LentiviralU2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29. expression of mutant U2AF1 in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE U2AF1 FP793, RN, RNU2AF1, U2AF35, U2AFBP Add to Cart
84019pRRL_U2AF1_S34F_mCherryU2AF1 (Homo sapiens)Mammalian Expression, LentiviralU2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015 Jan;25(1):14-26. doi: 10.1101/gr.181016.114. Epub 2014 Sep 29. expression of mutant U2AF1 in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE U2AF1 FP793, RN, RNU2AF1, U2AF35, U2AFBP Add to Cart
84020pRRL_SRSF2_WT_mCherrySRSF2 (Homo sapiens)Mammalian Expression, LentiviralSRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006. expression of SRSF2 in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b Add to Cart
84021pRRL_SRSF2_P95R_mCherrySRSF2 (Homo sapiens)Mammalian Expression, LentiviralSRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006. expression of SRSF2 mutant in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b Add to Cart
84022pRRL_SRSF2_P95L_mCherrySRSF2 (Homo sapiens)Mammalian Expression, LentiviralSRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006. expression of SRSF2 mutant in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b Add to Cart
84023pRRL_SRSF2_P95H_mCherrySRSF2 (Homo sapiens)Mammalian Expression, LentiviralSRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Cancer Cell. 2015 May 11;27(5):617-30. doi: 10.1016/j.ccell.2015.04.006. expression of SRSF2 mutant in mammalian cells pRRLSIN.cPPT.PGK-GFP.WPRE SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b Add to Cart