Thomas Roberts Lab Plasmids
The Thomas Roberts Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving life science research.
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|DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism.||Furman C, Short SM, Subramanian RR, Zetter BR, Roberts TM||J Biol Chem. 2002 Mar 8. 277(10):7962-9.|
|Constitutive cellular expression of PI 3-kinase is distinct from transient expression.||Auger KR, Wang J, Narsimhan RP, Holcombe T, Roberts TM||Biochem Biophys Res Commun. 2000 Jun 16. 272(3):822-9.|
|Induction of p53-independent apoptosis by simian virus 40 small t antigen.||Gjoerup O, Zaveri D, Roberts TM||J Virol. 2001 Oct . 75(19):9142-55.|
|Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase.||Zhao JJ, Gjoerup OV, Subramanian RR, Cheng Y, Chen W, Roberts TM, Hahn WC||Cancer Cell. 2003 May . 3(5):483-95.|
|PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis.||Ilic N, Utermark T, Widlund HR, Roberts TM||Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):E699-708. Epub 2011 Aug 29.|