Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin.

Yu K, Zhu J, Qu Z, Cui YY, Hartzell HC
J Gen Physiol. 2014 Feb;143(2):253-67. doi: 10.1085/jgp.201311047. Epub 2014 Jan 13. PubMed Article

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