PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway.

Hinoi E, Iezaki T, Fujita H, Watanabe T, Odaka Y, Ozaki K, Yoneda Y
Biochem Biophys Res Commun. 2014 Jul 18;450(1):255-60. doi: 10.1016/j.bbrc.2014.05.108. Epub 2014 Jun 2. PubMed Article

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