Parkinson-causing alpha-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation.

Dettmer U, Newman AJ, Soldner F, Luth ES, Kim NC, von Saucken VE, Sanderson JB, Jaenisch R, Bartels T, Selkoe D
Nat Commun. 2015 Jun 16;6:7314. doi: 10.1038/ncomms8314. PubMed Article

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