Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.

Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE
J Leukoc Biol. 2015 Dec;98(6):963-74. doi: 10.1189/jlb.2VMA0515-229RR. Epub 2015 Aug 26. PubMed Article

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