Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver.
Grimm D, Wang L, Lee JS, Schurmann N, Gu S, Borner K, Storm TA, Kay MA
J Clin Invest. 2010 Sep;120(9):3106-19. doi: 10.1172/JCI43565. Epub 2010 Aug 9.
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