Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.
Papa A, Wan L, Bonora M, Salmena L, Song MS, Hobbs RM, Lunardi A, Webster K, Ng C, Newton RH, Knoblauch N, Guarnerio J, Ito K, Turka LA, Beck AH, Pinton P, Bronson RT, Wei W, Pandolfi PP
Cell. 2014 Apr 24;157(3):595-610. doi: 10.1016/j.cell.2014.03.027.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
No plasmids are currently publicly available from Addgene for this article.