Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

Verma R, Peters NR, D'Onofrio M, Tochtrop GP, Sakamoto KM, Varadan R, Zhang M, Coffino P, Fushman D, Deshaies RJ, King RW
Science 2004 Oct 1;306(5693):117-20. PubMed Article

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