Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J
Nature. 2016 Jul 6;535(7610):153-8. doi: 10.1038/nature18629.
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PubMed
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 80950 | Flag-Gsdmd | Expresses Gsdmd in mammalian cells |
| 80951 | Flag-Gsdmd-NT | Expresses Gsdmd-NT in mammalian cells |
| 80952 | Flag-Gsdmd-NT 4A | Expresses Gsdmd-NT 4A mutant in mammalian cells |
| 80953 | Flag-Gsdmd-CT | Expresses Gsdmd-CT in mammalian cells |
| 133887 | Flag-Gsdmd-NT C39A | Expresses Gsdmd-NT mutant in mammalian cells |
| 133888 | Flag-Gsdmd-NT C57A | Expresses Gsdmd-NT mutant in mammalian cells |
| 133889 | Flag-Gsdmd-NT C77A | Expresses Gsdmd-NT mutant in mammalian cells |
| 133890 | Flag-Gsdmd-NT C122A | Expresses Gsdmd-NT mutant in mammalian cells |
| 133891 | Flag-Gsdmd-NT C192A | Expresses Gsdmd-NT mutant in mammalian cells |
| 133892 | Flag-Gsdmd-NT C265A | Expresses Gsdmd-NT mutant in mammalian cells |