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A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from PML-induced Senescence.
Acevedo M, Vernier M, Mignacca L, Lessard F, Huot G, Moiseeva O, Bourdeau V, Ferbeyre G
Cancer Res. 2016 Jun 1;76(11):3252-64. doi: 10.1158/0008-5472.CAN-15-2347. Epub 2016 Mar 29.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
73549shNTCNon-targeting control shRNA cloned in retroviral vector pMLP (MSCV-based vector expressing shRNA in a mir30 context).
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73550shCDK4(1)shRNA(1) against CDK4
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73551shCDK4(2)shRNA(2) against CDK4
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73552shCDK6(1)shRNA(1) against CDK6
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73553shCDK6(2)shRNA(2) against CDK6
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73554shCDK4/6(1)vector encoding both shRNA against CDK4(1) and shRNA against CDK6(1)
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73555shCDK4/6(2)vector encoding both shRNA against CDK4(2) and shRNA against CDK6(2)
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73556PML-ER-pBabevector encoding a fusion protein between PML-IV and ER (estrogen receptor)
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73557CDK2-3XFlag-pBabevector encoding a fusion protein between CDK2 and 3 Flag tags
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73558CDK4-3XFlag-pBabevector encoding a fusion protein between CDK4 and 3 Flag tags
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73559CDK4mut(K35M)-3XFlag-pBabevector encoding a fusion protein between a CDK4 mutant (K35M) and 3 Flag tags
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735603XFlag-pLPCvector encoding 3 Flag tags
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