IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation.
Ikink GJ, Boer M, Bakker ER, Hilkens J
Nat Commun. 2016 Nov 23;7:13567. doi: 10.1038/ncomms13567.
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