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IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact.

Bonneau B, Ando H, Kawaai K, Hirose M, Takahashi-Iwanaga H, Mikoshiba K
Elife. 2016 Dec 20;5. pii: e19896. doi: 10.7554/eLife.19896. (Link opens in a new window) PubMed (Link opens in a new window) Article

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