Kruppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions.
Segura MF, Jubierre L, Li S, Soriano A, Koetz L, Gaziel-Sovran A, Masanas M, Kleffman K, Dankert JF, Walsh MJ, Hernando E
Oncotarget. 2017 Apr 18;8(16):26298-26311. doi: 10.18632/oncotarget.15459. PubMed Article
Segura MF, Jubierre L, Li S, Soriano A, Koetz L, Gaziel-Sovran A, Masanas M, Kleffman K, Dankert JF, Walsh MJ, Hernando E
Oncotarget. 2017 Apr 18;8(16):26298-26311. doi: 10.18632/oncotarget.15459. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 100126 | pGL4-Cluster Promoter Delta 1 | It contains ~1.4Kb of the miR-183/96-182 cluster promoter |
| 100127 | pGL4-Cluster Promoter Delta 2 | It contains ~4.8 Kb of the miR-183-96-182 cluster promoter |
| 100128 | pGL4-Cluster Promoter Delta 3 | It contains ~2.7 Kb of the miR-183-96-182 cluster promoter |
| 100129 | pGL4-Cluster Promoter Delta 1.1 | It contains ~0.8 Kb of the miR-183-96-182 cluster promoter. Is the minimal region that contains the maximal promoter activity |
| 100130 | pGL4 Cluster Promoter Delta 1.2 | It contains 0.5 Kb of the miR-183-96-182 cluster promoter. This fragment partially loses promoter activity in melanoma cells. |
| 100131 | pEIGW-human KLF4 | Human KLF4 lentiviral expression vector |