Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells.

Zhang SL, Zhang W, Yang Z, Hu X, Tam KY
Eur J Pharm Sci. 2017 Mar 24. pii: S0928-0987(17)30165-3. doi: 10.1016/j.ejps.2017.03.030. PubMed Article

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