A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.
Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD
Nat Commun. 2017 Jun 28;8(1):39. doi: 10.1038/s41467-017-00049-x.
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