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A genetically encoded tool for manipulation of NADP+/NADPH in living cells.

Cracan V, Titov DV, Shen H, Grabarek Z, Mootha VK
Nat Chem Biol. 2017 Aug 7. doi: 10.1038/nchembio.2454. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
87853pUC57-TPNOXThis plasmid contains human codon optimized sequence of Lactobacillus brevis mutant of a water-forming oxidase that can be used to increase NADP+/NADPH ratio in mammalian cells.
87854pUC57-mitoTPNOXThis plasmid contains human codon optimized sequence of Lactobacillus brevis mutant of a water-forming oxidase that can be used to increase NADP+/NADPH ratio in mammalian cells.

Antibodies from Article