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ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase.

Chi X, Britt EC, Shows HW, Hjelmaas AJ, Shetty SK, Cushing EM, Li W, Dou A, Zhang R, Davies BSJ
Mol Metab. 2017 Oct;6(10):1137-1149. doi: 10.1016/j.molmet.2017.06.014. Epub 2017 Jun 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
109111pHS18 (mANGPTL3-Strep)Expresses StrepII-tagged mouse ANGPTL3 in mammalian cells
109112pHS15 (hANGPTL3-Strep)Expresses StrepII-tagged human ANGPTL3 in mammalian cells
109113pWL1 (mANGPTL8-V5-His)Expresses V5 and His-tagged mouse ANGPTL8 in mammalian cells
109114pEB30 (hANGPTL8-V5-His)Expresses V5 and His-tagged human ANGPTL8 in mammalian cells
109115pEB5 (mANGPTL8-V5-His lenti)V5 and His-tagged mouse ANGPTL8 in a lentiviral vector
109116pEB31 (hANGPTL8-V5-His lenti)V5 and His-tagged human ANGPTL8 in a lentiviral vector
257784pEB2 (mANGPLT3 1-221 -Strep)Expresses truncated (aa 1-221) and Strep-tagged mouse ANGPTL3 in mammalian cells
257785pEB29 (C-terminal mANGPTL3 -Strep)Expresses the C-terminal fibrinogen-like domain of mouse ANGPTL3 in mammalian cells. Contains signal peptide and is Strep tagged.

Antibodies from Article