Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.
Liu Z, Lu Z, Yang G, Huang S, Li G, Feng S, Liu Y, Li J, Yu W, Zhang Y, Chen J, Sun Q, Huang X
Nat Commun. 2018 Jun 14;9(1):2338. doi: 10.1038/s41467-018-04768-7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 107720 | pUC57-Sa sgRNA expression vector | For in vitro transcription of Sa sgRNA from the T7 promoter. |
| 107721 | pGL3-U6-sgRNA-EGFP | For expression of sgRNA from the U6 promoter with EGFP expression simultaneously |
| 107722 | pGL3-U6-sgRNA-BFP | For expression of sgRNA from the U6 promoter with BFP expression simultaneously |
| 107723 | pCMV-ABE | For expression of ABE7.10 in mammalian cells |