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Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes.

Jelluma N, Brenkman AB, McLeod I, Yates JR 3rd, Cleveland DW, Medema RH, Kops GJ
PLoS One. 2008 Jun 11;3(6):e2415. doi: 10.1371/journal.pone.0002415. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
114065pFastBac-GST-Mps1-WTprotein production
114066pFastBac-GST-Mps1-KDprotein production

Antibodies from Article