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Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II.

Nagashima R, Hibino K, Ashwin SS, Babokhov M, Fujishiro S, Imai R, Nozaki T, Tamura S, Tani T, Kimura H, Shribak M, Kanemaki MT, Sasai M, Maeshima K
J Cell Biol. 2019 Mar 1. pii: jcb.201811090. doi: 10.1083/jcb.201811090. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
124495POLR2A-N CRISPR pX330A CRISPR plasmid for targeting the N-terminus coding region of human POLR2A
124496mAC-POLR2A donor (Hygro)A donor plasmid for tagging the N-terminus of human POLR2A with mAID-mClover
247344pEF-1α-Venus-Nup107-FRTExpresses Venus-NUP107 under EF1 promoter and can be integrated into FRT site
247345pPB-CAG-IB-H2B-HaloTagExpresses H2B-Halo under CAG promoter and can be randomly integrated by PiggyBac transposase

Antibodies from Article