Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.

Mir A, Alterman JF, Hassler MR, Debacker AJ, Hudgens E, Echeverria D, Brodsky MH, Khvorova A, Watts JK, Sontheimer EJ
Nat Commun. 2018 Jul 6;9(1):2641. doi: 10.1038/s41467-018-05073-z. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.