In vitro-transcribed guide RNAs trigger an innate immune response via the RIG-I pathway.

Wienert B, Shin J, Zelin E, Pestal K, Corn JE
PLoS Biol. 2018 Jul 16;16(7):e2005840. doi: 10.1371/journal.pbio.2005840. eCollection 2018 Jul. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.