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Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway.

Bugaj LJ, Sabnis AJ, Mitchell A, Garbarino JE, Toettcher JE, Bivona TG, Lim WA
Science. 2018 Aug 31;361(6405). pii: 361/6405/eaao3048. doi: 10.1126/science.aao3048. (Link opens in a new window) PubMed (Link opens in a new window) Article

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