NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway.

Hafner-Bratkovic I, Susjan P, Lainscek D, Tapia-Abellan A, Cerovic K, Kadunc L, Angosto-Bazarra D, Pelegrin P, Jerala R
Nat Commun. 2018 Dec 5;9(1):5182. doi: 10.1038/s41467-018-07573-4. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.