The neurosteroid pregnenolone promotes degradation of key proteins in the innate immune signaling to suppress inflammation.

Murugan S, Jakka P, Namani S, Mujumdar V, Radhakrishnan G
J Biol Chem. 2019 Mar 22;294(12):4596-4607. doi: 10.1074/jbc.RA118.005543. Epub 2019 Jan 15. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.