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Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons.
Ahfeldt T, Ordureau A, Bell C, Sarrafha L, Sun C, Piccinotti S, Grass T, Parfitt GM, Paulo JA, Yanagawa F, Uozumi T, Kiyota Y, Harper JW, Rubin LL
Stem Cell Reports. 2019 Dec 20. pii: S2213-6711(19)30444-8. doi: 10.1016/j.stemcr.2019.12.005.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
135814pTAHR TH-p2a-TD:Tomato (floxed selection Puro)Fluorescent reporter for knock-in of TdTomato into the TH locus
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135815pTACR TH1-p2aGFPCRISPR based on px330 p2aGFP targeting TH gene near stop codon
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135816pTACR TH2-p2aGFPCRISPR based on px330 p2aGFP targeting TH gene near stop codon
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Antibodies from Article