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Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures.
Billon P, Nambiar TS, Hayward SB, Zafra MP, Schatoff EM, Oshima K, Dunbar A, Breinig M, Park YC, Ryu HS, Tschaharganeh DF, Levine RL, Baer R, Ferrando A, Dow LE, Ciccia A
Cell Rep. 2020 Mar 10;30(10):3280-3295.e6. doi: 10.1016/j.celrep.2020.02.068.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
139321sgRNA BRCA2 V572IPlasmid expressing a sgRNA to introduce BRCA2 V572I using base editing
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139322sgRNA BRCA2 V2102IPlasmid expressing a sgRNA to introduce BRCA2 V2102I using base editing
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139323sgRNA BRCA2 E2772KPlasmid expressing a sgRNA to introduce BRCA2 E2772K using base editing
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139324sgRNA BRCA2 R2842CPlasmid expressing a sgRNA to introduce BRCA2 R2842C using base editing
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139325sgRNA BRCA2 S3070FPlasmid expressing a sgRNA to introduce BRCA2 S3070F using base editing
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139326sgRNA BRCA1 C64YPlasmid expressing a sgRNA to introduce BRCA1 C64Y using base editing
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139327sgRNA BRCA1 E638KPlasmid expressing a sgRNA to introduce BRCA1 E638K using base editing
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139328sgRNA BRCA1 T922IPlasmid expressing a sgRNA to introduce BRCA1 T922I using base editing
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139329sgRNA BRCA1 S1363LPlasmid expressing a sgRNA to introduce BRCA1 S1363L using base editing
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139330sgRNA BRCA1 E1754KPlasmid expressing a sgRNA to introduce BRCA1 E1754K using base editing
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139331sgRNA BRCA1 Q1779StopPlasmid expressing a sgRNA to introduce BRCA1 Q1779Stop using base editing
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139332sgRNA FANCD2 Q223StopPlasmid expressing a sgRNA to introduce FANCD2 Q223Stop using base editing
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139333DTECT - Plasmid for Standard CurveThis plasmid is used to generate the unique standard curve required to quantify the capture of genomic signature using DTECT
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139511sgRNA BRCA2 R2896CPlasmid expressing a sgRNA to introduce BRCA2 R2896C using base editing
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