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Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X
Nat Neurosci. 2019 Mar;22(3):386-400. doi: 10.1038/s41593-019-0338-y. Epub 2019 Feb 11.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
15785961426-hU6-shmFmr1-EF1a-mCherryExpresses a shRNA targeting mouse Fmr1 gene
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15786061427-sgHtt_6Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system
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15786161427-sgHtt_10Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system
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Recombinant Antibodies from Article