In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy.
Colasante G, Qiu Y, Massimino L, Di Berardino C, Cornford JH, Snowball A, Weston M, Jones SP, Giannelli S, Lieb A, Schorge S, Kullmann DM, Broccoli V, Lignani G
Brain. 2020 Mar 1;143(3):891-905. doi: 10.1093/brain/awaa045.
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No plasmids are currently publicly available from Addgene for this article.