Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS

Alexis A. Jourdain, Bridget E. Begg, Eran Mick, Hardik Shah, Sarah E. Calvo, Owen S. Skinner, Rohit Sharma, Steven M. Blue, Gene W. Yeo, Christopher B. Burge, Vamsi K. Mootha 8
Molecular Cell Article

Plasmids from Article

ID	Plasmid	Purpose
165925	pLENTICRISPR-ACIN1-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of ACIN1
165926	pLENTICRISPR-ACIN1-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of ACIN1
165927	pLENTICRISPR-ENO1-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of ENO1
165928	pLENTICRISPR-ENO1-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of ENO1
165929	pLENTICRISPR-HK2-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of HK2
165930	pLENTICRISPR-HK2-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of HK2
165931	pLENTICRISPR-HNRNPD-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of HNRNPD
165932	pLENTICRISPR-HNRNPD-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of HNRNPD
165933	pLENTICRISPR-LUC7L-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of LUC7L
165934	pLENTICRISPR-LUC7L-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of LUC7L
165935	pLENTICRISPR-LUC7L2-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of LUC7L2
165936	pLENTICRISPR-LUC7L2-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of LUC7L2
165937	pLENTICRISPR-LUC7L3-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of LUC7L3
165938	pLENTICRISPR-LUC7L3-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of LUC7L3
165939	pLENTICRISPR-NDUFB5-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of NDUFB5
165940	pLENTICRISPR-NDUFB5-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of NDUFB5
165941	pLENTICRISPR-PABPC1-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of PABPC1
165942	pLENTICRISPR-PABPC1-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of PABPC1
165943	pLENTICRISPR-PGAM1-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of PGAM1
165944	pLENTICRISPR-PGAM1-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of PGAM1
165945	pLENTICRISPR-SNRNP70-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of SNRNP70
165946	pLENTICRISPR-SNRNP70-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of SNRNP70
165947	pLENTICRISPR-SNRPA-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of SNRPA
165948	pLENTICRISPR-SNRPA-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of SNRPA
165949	pLENTICRISPR-TPI1-sgRNA1	CRISPR-mediated gene perturbation (knock-out) of TPI1
165950	pLENTICRISPR-TPI1-sgRNA2	CRISPR-mediated gene perturbation (knock-out) of TPI1
165951	pLV-EF1a-IRES-puro-GFP-3xFLAG	Overexpression of GFP.
165952	pLV-EF1a-IRES-puro-LUC7L2-3xFLAG	Overexpression of LUC7L2.
165953	pLV-EF1a-IRES-puro-PFKM	Overexpression of PFKM.
165954	pWPI-Neo-GFP	Overexpression of GFP.
165955	pWPI-Neo-LUC7L-3xFLAG	Overexpression of LUC7L.
165958	pWPI-Neo-SLC7A11-HA	Overexpression of SLC7A11.