Activation of endogenous retroviruses during brain development causes an inflammatory response.
Jonsson ME, Garza R, Sharma Y, Petri R, Sodersten E, Johansson JG, Johansson PA, Atacho DA, Pircs K, Madsen S, Yudovich D, Ramakrishnan R, Holmberg J, Larsson J, Jern P, Jakobsson J
EMBO J. 2021 Mar 1:e106423. doi: 10.15252/embj.2020106423. PubMed Article
Jonsson ME, Garza R, Sharma Y, Petri R, Sodersten E, Johansson JG, Johansson PA, Atacho DA, Pircs K, Madsen S, Yudovich D, Ramakrishnan R, Holmberg J, Larsson J, Jern P, Jakobsson J
EMBO J. 2021 Mar 1:e106423. doi: 10.15252/embj.2020106423. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 170363 | pLV.U6gLacZ.EFS-NS.H2B-RFP | Negative control plasmid used for Crispr/cas9 based disruption. Expressing nuclear RFP. |
| 170364 | pLV.U6gT28.3.EFS-NS.H2B-RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 3. Expressing nuclear RFP. |
| 170365 | pLV.U6gT28.4.EFS-NS.H2B-RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 4. Expressing nuclear RFP. |
| 170367 | pAAV.hSyn.Cre | AAV vector expressing Cre under human synapsin promotor |
| 170368 | pAAV.hSyn.flex.H2B.GFP | Cre-inducible AAV vector expressing nuclear GFP. |
| 170369 | pAAV.U6gLacZ.hSyn.H2B.RFP | Negative control plasmid used for Crispr/cas9 based disruption. Expressing nuclear RFP. |
| 170370 | pAAV.U6gT28.3.hSyn.H2B.RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 3. Expressing nuclear RFP. |
| 170372 | pAAV.U6gT28.13.hSyn.H2B.RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 13. Expressing nuclear RFP. |
| 170373 | pAAV.U6gLacZ.hSyn.flex.H2B.RFP | Negative control guide, Cre-inducible plasmid expressing nuclear RFP. |
| 170374 | pAAV.U6gT28.3.hSyn.flex.H2B.RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 3. Cre-inducible expression of nuclear RFP. |
| 170376 | pAAV.U6gT28.13.hSyn.flex.H2B.RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 13. Cre-inducible expression of nuclear RFP. |
| 170386 | pAAV.U6gT28.4.hSyn.flex.H2B.RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 4. Cre-inducible expression of nuclear RFP. |
| 170387 | pAAV.U6gT28.4.hSyn.H2B.RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 4. Expressing nuclear RFP. |
| 170388 | pLV.U6gT28.13.EFS-NS.H2B-RFP | Plasmid used for Crispr/cas9 based disruption of mouse Trim28, guide targeting exon 13. Expressing nuclear RFP. |