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Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression.
Campbell AE, Dyle MC, Albanese R, Matheny T, Sudheendran K, Cortazar MA, Forman T, Fu R, Gillen AE, Caruthers MH, Floor SN, Calviello L, Jagannathan S
Cell Rep. 2023 Jun 13;42(6):112642. doi: 10.1016/j.celrep.2023.112642. PubMed Article

Plasmids from Article

ID Plasmid Purpose
171951pCW57.1-FLAG-SRSF3_Full.Length_Codon.Optimized-BlastAll-in-one lentiviral vector for doxycycline-inducible expression of FLAG-tagged, codon-optimized, full-length SRSF3
171952pCW57.1-FLAG-SRSF3_Truncated_Codon.Optimized-BlastAll-in-one lentiviral vector for doxycycline-inducible expression of FLAG-tagged, codon-optimized, truncated SRSF3
172345pTwist-FLAG-SRSF3_Full.Length_Codon.OptimizedExpression of FLAG-tagged, codon-optimized, full-length SRSF3
172346pTwist-FLAG-SRSF3_Truncated_Codon.OptimizedExpression of FLAG-tagged, codon-optimized, truncated SRSF3

Antibodies from Article