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Highly efficient and safe genome editing by CRISPR-Cas12a using CRISPR RNA with a ribosyl-2'-O-methylated uridinylate-rich 3'-overhang in mouse zygotes.

Ha DI, Lee JM, Lee NE, Kim D, Ko JH, Kim YS
Exp Mol Med. 2020 Nov;52(11):1823-1830. doi: 10.1038/s12276-020-00521-7. Epub 2020 Nov 9. (Link opens in a new window) PubMed (Link opens in a new window) Article

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