Tumor sequencing is useful to refine the analysis of germline variants in unexplained high-risk breast cancer families.

Van Marcke C, Helaers R, De Leener A, Merhi A, Schoonjans CA, Ambroise J, Galant C, Delree P, Rothe F, Bar I, Khoury E, Brouillard P, Canon JL, Vuylsteke P, Machiels JP, Berliere M, Limaye N, Vikkula M, Duhoux FP
Breast Cancer Res. 2020 Apr 15;22(1):36. doi: 10.1186/s13058-020-01273-y. PubMed Article

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